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Steele CJ, Anwander A, Bazin P, Trampel R, Schaefer A, Turner R, Ramnani N, Villringer A (2017) Human cerebellar sub-millimeter diffusion imaging reveals the motor and non-motor topography of the dentate nucleus. Cerebral Cortex, 27(9):4537-4548    
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Abstract
The reciprocal cortico-cerebellar loops that underlie cerebellar contributions to motor and cognitive behavior form one of the largest systems in the primate brain. Work with non-human primates has shown that the dentate nucleus, the major output nucleus of the cerebellum, contains topographically distinct connections to both motor and non-motor regions, yet there is no evidence for how the cerebellar cortex connects to the dentate nuclei in humans. Here we used in-vivo sub-millimeter diffusion imaging to characterize this fundamental component of the cortico-cerebellar loop, and identified a pattern of superior motor and infero-lateral non-motor connectivity strikingly similar to that proposed by animal work. Crucially, we also present first evidence that the dominance for motor connectivity observed in non-human primates may be significantly reduced in man – a finding that is in accordance with the proposed increase in cerebellar contributions to higher cognitive behavior over the course of primate evolution